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Clinical Ageing Research Unit (CARU)

The Clinical Ageing Research Unit (CARU) is a £5.5 million clinical research facility funded by the Wellcome Trust and Wolfson Foundation.CARU building

We opened in September 2008 and are located on the University’s Campus for Ageing and Vitality.

Our primary aim is to facilitate the development of early assessment and intervention strategies targeted at age-associated degenerative conditions.

The Unit Director for CARU is Prof. Nicola Pavese. He is Professor of Clinical Neuroscience at NU and Consultant Neurologist at NuTH. He has >30 years of experience in leading a range of experimental medicine and clinical trials in Parkinson’s disease (PD) and other neurodegenerative disorders, including the use of neuroimaging to evaluate the bio-distribution and metabolism of new therapies. He leads an international programme to identify early biomarkers of PD and related movement disorders.

We provide a high quality, patient-friendly environment for phase II-IV clinical studies in the older patient. We employ experienced research nurses with specific training in commonly used, relevant assessment instruments.

Clinical trials are supported by a high quality research infrastructure, embedded within the joint Acute Trust-University research system, with a study coordinator and data manager located on site.

We work closely with the NIHR Newcastle Biomedical Research Centre, which aims to improve lives through world-class research into ageing syndromes and long-term conditions.

Our facilities support their research, particularly the following areas:

  • Dementia
  • Parkinson’s and other neurodegenerative conditions
  • Movement disorders
  • Mitochondrial disorders
  • Sarcopenia (loss of muscle strength and mass)
  • Other ageing syndromes, such as cardiovascular ageing and visual failure

CARU has a key role in delivering studies falling within these research themes.

Partners and funding

In conjunction with the NIHR Research Design Service North East, Newcastle University, NUTH and CNTW colleagues, the Clinical Ageing Research Unit (CARU) at Newcastle provides a ‘one stop shop’ for investigators planning, designing, conducting and analysing trials and other high quality clinical research studies.